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Practice Guideline
for the Treatment of Post-traumatic Stress Disorder
International Society for Traumatic Stress Studies (ISTSS)
INTRODUCTION
This practice guideline was developed under the auspices
of the PTSD Treatment Guidelines Task Force established by
the Board of Directors of the International Society for Traumatic
Stress Studies (ISTSS) in November, 1997. The guideline is
intended to inform the clinician on treatment of individuals
with a diagnosis of post-traumatic stress disorder (PTSD).
PTSD is a serious psychological condition that occurs as a
result of experiencing a traumatic event. The symptoms that
characterize PTSD are: reliving the traumatic event or frightening
elements of it, avoidance of thoughts, memories, people, and
places associated with the event, emotional numbing, and symptoms
of elevated arousal. Often accompanied by other psychological
disorders, PTSD is a complex condition that can be associated
with significant morbidity, disability, and impairment of
life functions.
In the development of this guideline, the Task Force recognized
that traumatic experiences can lead to the development of
several different disorders, including major depression, specific
phobias, personality disorders such as borderline anxiety
disorder, and panic disorder. Yet the focus of this guideline
is specifically on the treatment of PTSD and its symptoms
as defined in the Diagnostic and Statistical Manual (DSM)
of the American Psychiatric Association (IV Edition, 1994).
The Task Force also recognized that PTSD is often accompanied
by other psychological conditions and that such comorbidity
requires clinical sensitivity, attention, and evaluation at
the point of diagnosis and throughout the process of treatment.
Disorders of particular concern are substance abuse and major
depression, the most frequently co-occurring conditions. Practitioners
are referred to the guidelines for these disorders in the
development of treatment plans for individuals who manifest
multiple disorders.
The guideline is intended for adults, adolescents, and children
who have developed PTSD. Its objective is to assist the clinician
in providing treatment to these individuals. Because clinicians
with diverse professional backgrounds provide mental health
treatment for PTSD, the guideline was developed with interdisciplinary
input. Psychologists, psychiatrists, social workers, creative
arts therapists, marital therapists, and others, actively
contributed to, and participated in, the developmental process.
Accordingly, the guideline is suitable for the diversity of
clinicians that treat PTSD.
The Task Force explicitly excluded from consideration in
this guideline individuals who are embedded within ongoing
violent or abusive relationships. It is recognized that children
who are living with an abusive caregiver, women or men who
are currently targets of domestic abuse or violence, and those
still living in a war-zone, may well meet diagnostic criteria
for PTSD. Yet, the treatment of these individuals, as well
as related forensic and ethical issues, are fundamentally
different from those of individuals whose traumatic events
have terminated. Therefore, individuals who are in the midst
of a traumatic situation require special considerations from
the clinician. Other practice guidelines will need to be developed
for these circumstances.
Little is known about the treatment of PTSD in non-industrialized
countries. Research and scholarly treatises on the topic come
largely from the Western industrialized nations. The Task
Force acknowledges this cultural limitation explicitly. There
is growing recognition that PTSD is a universal response to
exposure to traumatic events which is observed in many different
cultures and societies. Yet, there is a need for systematic
research to determine the extent to which the treatments,
both psychological and psychopharmacological, that have proven
efficacy in Western societies are effective in non-Western
cultures.
Finally, the clinician who follows this guideline should
not limit him/herself to the approaches and techniques included
herein. Creative integration of new approaches, that have
been found to be helpful in other conditions and that have
a theoretically sound foundation, are encouraged in an effort
to optimize treatment outcome.
DEVELOPMENT PROCESS
The process of developing the guideline was as follows. The
Task Force co-chairs assembled the Task Force by identifying
experts in the major schools of therapy and treatment modalities
that are currently employed with patients who suffer from
PTSD. The Task Force was expanded as additional relevant treatment
approaches were identified. Thus, the Task Force represented
experts across approaches, theoretical orientations, schools
of therapy, and professional training. The focus of the guideline
and its format was determined by the Task Force in a series
of meetings.
The Task Force co-chairs commissioned position papers on
the major treatment areas or modalities from Task Force members.
Each paper was to be written by a designated member with assistance
from other members or clinicians, as deemed necessary by that
member. The position papers included literature review of
research and clinical practice.
The literature reviews on each of the topics involved the
use of on-line literature searches such as Published International
Literature on Traumatic Stress (PILOTS), MedLine, and PsychLit.
The papers adhere to a standard format and were restricted
in length. Authors reviewed the literature in their assigned
area, presented the clinical findings, reviewed critically
the scientific support for the approach, and presented the
papers to the Chairs. Completed papers were then distributed
to all Task Force members for comments and active discussion.
On the basis of the position papers, and careful attention
to the literature review, a draft of practice guideline for
each treatment approach was developed. In this guideline,
each treatment approach or modality was assigned ratings with
respect to strength of evidence regarding its efficacy. These
ratings were standardized, using a coding system adapted from
the Agency for Health Care Policy and Research (AHCPR; U.S.
Department of Health and Human Services, Public Health Service).
This rating system, presented below, represents an effort
to formulate recommendations for practitioners based on the
available scientific evidence.
The guideline was reviewed by all members of the Task Force
for concurrence, and was then presented to the Board of Directors
of the ISTSS, sent for review to a broad range of professional
associations, was presented at a public forum at the annual
meeting of the ISTSS, and placed on the ISTSS web-site for
comments from the membership. Feedback obtained from this
iterative process was incorporated into the guideline with
the concurrence.of the Task Force.
CLINICAL ISSUES
Type of Trauma
Most randomized clinical trials (RCTs) with combat (mostly
Vietnam) veterans showed inferior treatment efficacy than
RCTs with non-veterans whose PTSD is related to other traumatic
experiences (e.g., sexual assaults, accidents, natural disasters)
. Therefore, some experts believe that combat veterans with
PTSD are less responsive to treatment than victims of other
traumas. Such a conclusion is premature. The difference between
veterans and other PTSD patients may be related to the greater
severity and chronicity of their PTSD rather than to differences
inherent to combat traumas. Furthermore, the poor treatment
response in veterans may be a sampling artifact since veterans
currently receiving treatment at VA hospitals may constitute
a self-selected group of chronic patients with multiple impairments.
In short, there is no conclusive evidence at this time that
PTSD following certain traumas is especially resistant to
treatment.
Single vs. Multiple Traumas
No clinical studies have been designed to address the question
of whether the number of previous traumas predicts treatment
response among PTSD patients. Since most treatment studies
have been carried out on either military veterans or female
adult survivors of sexual assault, many of whom with history
of multiple assault, it appears that much of the current knowledge
about treatment efficacy applies to people who have been traumatized
more than once. It would be of great interest to conduct studies
comparing individuals with single vs. multiple traumas in
order to find out whether, as expected, the former would be
more responsive to treatment. Recruitment for such studies
could be very difficult, however, since the research design
would have to control for PTSD severity and chronicity, as
well as for comorbid diagnoses -- each of which may be more
predictive of treatment response than number of traumas experienced.
Chronicity of PTSD
There is growing interest in clinical approaches that emphasize
prevention, identification of risk factors, early detection
of PTSD, and acute intervention. This is because of the idea
that, as with many medical and mental disorders, PTSD has
a better prognosis if clinical intervention is implemented
as early as possible. However, the few studies available to
date do not support this view. On the other hand, there is
abundant evidence that many people who develop PTSD continue
to suffer from the disorder indefinitely. Although it is unclear
whether chronic PTSD is inherently (e.g., psychobiologically)
different than more acute clinical presentations, it is generally
believed that chronic PTSD is more difficult to treat.
Some patients with chronic PTSD develop a persistent incapacitating
mental illness marked by severe and intolerable symptoms,
marital, social, and vocational disability as well as an extensive
use of psychiatric and community services. Such patients may
benefit more from case management and psycho-social rehabilitation
than from psycho- or pharmacotherapy (see Psycho-social Rehabilitation
chapter).
Gender
Although lifetime prevalence rates of PTSD are twice as high
for women as for men (10.4% vs. 5%) and women are four times
more likely to develop PTSD when exposed to the same trauma,
gender differences in response to treatment have not been
studied systematically. Therefore, we do not know whether
gender is predictive of treatment outcome. It is important
to emphasize this point since as we noted above, a superficial
review of the treatment literature suggests that women are
more responsive to treatment than men. On further inspection,
however, several differences between treatment studies with
men and women can be noted, making direct comparisons difficult.
First, the PTSD of women studied has usually been caused by
(childhood or adult) sexual trauma whereas studies with men
have usually involved war veterans. Second, since there is
very little data on men who are not Vietnam veterans, the
generalizability of published data regarding veterans to men
in general is questionable. Finally, other factors such as
treatment modality, PTSD severity/chronicity, or the presence
of comorbid disorders will need to be systematically controlled
in future studies before differences in treatment outcome
can be attributed to gender. In short, it is impossible to
conclude that gender is predictive of treatment response at
this time.
Age
Two questions are relevant concerning the effects of age
on treatment outcome: a) Does the age at which the trauma
occurred influence response to treatment? and b) Does the
age when treatment began affects treatment outcome? Neither
question has been studied systematically , hence there are
no conclusive data on either question. Adults and children
have responded to some treatments and not others. Age of traumatization
has not predicted treatment outcome in studies published to
date.
Children
Children present so many distinct challenges for assessment
and treatment, that an entire review has been devoted to treatment
of children with PTSD (see Chapter ??). Developmental level
is particularly important since it may influence both the
clinical phenomenology of PTSD in children as well as the
choice of treatment. In addition, parental factors must be
carefully considered when treating children. Developmental
biological factors may also influence choice of drug, if pharmacotherapy
is indicated, while developmental cognitive factors may influence
both assessment strategies and choice of psychotherapy.
Elder Adults
PTSD may have its onset or reoccurrence at any point in the
life cycle. It may persist for decades and even intensify
in old age. Developmental factors unique to older adults may
influence susceptibility to PTSD among the aged. These include
a sense of helplessness produced by illness, diminished functional
capacity, or social marginalization. Death of loved ones can
trigger intrusive recollections of traumatic losses, thereby
precipitating a relapse of PTSD symptoms that may have been
in remission for decades. Retirement and the life review process
of old age can also increase vulnerability to PTSD exacerbation
or relapse. Developmental biological factors may influence
both the choice and recommended dosage of any drug selected
for pharmacotherapy while cognitive status may influence the
approach to both assessment and psychotherapy for older PTSD
patients.
FACTORS AFFECTING DECISION FOR TREATMENT
Treatment Goals
All treatments presented in these practice guidelines have
proponents who claim that they are clinically useful for patients
with PTSD. The therapeutic goals for each treatment, however,
are not necessarily the same. Some treatments (e.g., CBT,
pharmacotherapy and EMDR) target PTSD symptom reduction as
the major clinical outcome by which efficacy should be judged.
Other treatments (e.g., hypnosis, art therapy, and possibly
psychoanalysis) emphasize the capacity to enrich the assessment
or therapeutic process rather than the ability to improve
PTSD symptoms. Still other treatments (e.g. psychosocial rehabilitation)
emphasize functional improvement with or without reduction
of PTSD symptoms. Finally, some interventions (e.g., hospitalization,
substance abuse treatment) focus primarily on disruptive behaviors
or comorbid disorders that must be controlled before PTSD
treatment per se can be initiated.
Treatment of PTSD
Treatment of PTSD is the major criterion by which all clinical
practices will be evaluated. Some treatments appear to reduce
all clusters of PTSD symptoms while others seem to be effective
in attenuating one symptom cluster (e.g., intrusion (B), avoidant/numbing
(C) or arousal (D) symptoms) but not others. The chapter on
assessment will discuss state-of-the-art methods for assessing
and monitoring PTSD symptom severity during a treatment trial.
Some experts have challenged the focus on specific symptoms
when evaluating various therapeutic approaches, arguing that
the best gauge of clinical efficacy is the capacity of a given
treatment to produce global improvement in PTSD rather than
specific symptom reduction. In this guideline, however, the
major criterion for treatment efficacy will be reduction of
PTSD symptoms although clinical global improvement will be
indicated when available.
Comorbidity
As with other mental disorders, patients with PTSD usually
have at least one other psychiatric disorder. Indeed, American
epidemiological findings indicate that 80% of patients with
lifetime PTSD suffer from lifetime depression, another anxiety
disorder or chemical abuse/dependency. Good clinical practice
dictates that the best treatment is one that might be expected
to ameliorate both PTSD and comorbid symptoms. Therefore,
the presence of a specific comorbid disorder may prompt a
clinician to choose one particular treatment rather than another.
This matter will be addressed in detail in the respective
Position Paper on each treatment approach. Again, it must
be emphasized, however, that treatment of PTSD is the major
criterion by which all clinical practices will be evaluated.
Suicidality
Self-destructive and impulsive behaviors, while not part
of the core PTSD symptom complex, are recognized as associated
features of this disorder that may profoundly affect clinical
management. Therefore, the routine assessment of all patients
presenting with PTSD should include a careful evaluation of
current suicidal ideation and the past history of suicidal
attempts. Risk factors for suicide should also be assessed
such as current depression and substance abuse. If significant
suicidality is present, it must be addressed before any other
treatment is initiated. If the patient cannot be safely managed
as an outpatient, hospitalization should be the immediate
clinical focus. If suicidality is secondary to depression
and/or substance abuse, clinical attention must focus on either
or both conditions, before initiating treatment for PTSD.
Chemical Abuse/Dependency
Lifetime prevalence rates of alcohol abuse/dependence among
men and women with PTSD are approximately 52% and 28%, respectively,
while prevalence rates for drug abuse/dependence are 35% and
27% respectively. Such comorbid disorders not only complicate
treatment, but in some cases might exacerbate PTSD itself.
In addition, a number of legal substances such as nicotine,
caffeine, and sympathomimetics (e.g., nasal decongestants)
may interfere with treatment and, therefore, should be carefully
assessed with all PTSD patients. In most cases, if significant
chemical abuse/dependency is present, it should be addressed
before PTSD treatment is initiated.
Concurrent General Medical Conditions
There is mounting evidence that people with PTSD appear to
be at greater risk of developing medical illnesses. Compared
to nontraumatized individuals, trauma survivors report more
medical symptoms, use more medical services, have more medical
illnesses detected during a physical examination and display
higher mortality. A few studies suggest that such adverse
medical consequences may be mediated by PTSD. This has generated
recent interest in screening primary and specialty medical
patients for both a trauma history and for PTSD symptoms.
This work is in its infancy, however, and there is no data
on treatment of PTSD among patients seeking medical or surgical
care.
Disability and Functional Impairment
PTSD sufferers differ greatly from one another with respect
to symptom severity, chronicity, complexity, comorbidity,
associated symptoms and functional impairment. These differences
may affect both the choice of treatment and the clinical goals.
For some patients with chronic PTSD, functional improvement
may be much more important than reduction of PTSD symptoms.
In others (especially those who have been subjected to protracted
child sexual abuse or torture), clinical interventions often
need to focus primarily on symptoms of dissociation, impulsivity,
affect lability, somatization, interpersonal difficulties,
or pathological changes in identity. Therefore, although the
major emphasis in this Practice Guideline is on reduction
of core PTSD symptoms, clinicians may find that functional
improvement is the most important or appropriate clinical
priority for some patients.
Indications for Hospitalization
Inpatient treatment should be considered when the individual
is in imminent danger of harming self or others, has destabilized
or relapsed significantly in the ability to function, is in
the throes of major psychosocial stressors, and/or is in need
of specialized observation/evaluation in a secure environment.
Elective hospitalization on a specialized inpatient treatment
program is reviewed at length in a position paper devoted
entirely to this topic (see Chapter ??). The general recommendation
is that such a hospitalization must occur in collaboration
with outpatient providers and be integrated into the overall
long-term treatment plan that has been developed. The basic
philosophy is that a focus on the past trauma is only in the
interest of the future. The goal of treatment is to facilitate
efforts to create a life that can move beyond the current
immobilization and preoccupation produced by the trauma.
GUIDELINE CONSIDERATIONS
What treatments are included in the Guideline?
The treatment for trauma-related disturbances has been discussed
extensively in the literature for over 100 years. This rich
literature has provided us with much clinical wisdom. In the
last two decades, several treatments for PTSD have been studied,
using experimental and statistical methods. Thus, at the present
time, we have both clinical and scientific knowledge about
what treatment modalities help patients with post-trauma problems.
Accordingly, the guidelines contain a variety of psychotherapies
and pharmacotherapies that have been practiced with trauma
victims who suffer trauma-related symptoms.
It is recognized that the scientific as well as clinical
evidence for the efficacy of these therapies in reducing PTSD
and related symptoms vary greatly from one another. However,
because the study of treatment efficacy for PTSD is still
in its initial stage relative to other mental disorders, the
Task Force decided to include in the guideline both therapies
that have been found effective by well controlled studies
as well as therapies that have been practiced but have not
yet been subjected to empirical testing.
What are Well Controlled Studies?
Many studies have been conducted to ascertain the efficacy
of various treatments in reducing PTSD, only relatively few
studies to date have employed rigorous methods. Well controlled
studies should have the following features.
Clearly-Defined Target Symptoms - Merely experiencing
a trauma is not an indication for treatment in and of itself.
Significant trauma-related symptoms, such as the presence
of PTSD or depression, should be present to justify treatment.
Whatever the target symptom or syndrome, it should be defined
clearly so that appropriate measures can be employed to assess
improvement. In addition to ascertaining diagnostic status,
it is also important to specify a threshold of symptom severity
as an inclusion criterion for entering treatment.
A related issue to target symptoms is the importance of delineating
inclusion and exclusion criteria. Delineation of inclusion/exclusion
criteria can be of assistance in examining predictors of outcome
as well in evaluating the efficacy of the treatment. If a
treatment is effective regardless of sample differences, it
proves more robust and therefore a more useful treatment.
Reliable and Valid Measures - Once target symptoms
have been identified and the population defined, measures
with good psychometric properties should be employed (see
earlier discussion on measures). For studies targeting a particular
diagnosis, assessment should include instruments designed
to yield diagnoses as well as instruments that assess symptom
severity.
Use of Blind Evaluators - Early studies of treatment
of trauma victims relied primarily on therapist and patient
reports to evaluate treatment efficacy. This introduces expectancy
and demand biases into the evaluation. The use of blind evaluators
is a current requirement for a credible treatment outcome
study. Two procedures are involved in keeping an evaluator
blind. First, the evaluator should not be the same person
conducting the treatment. Second, patients should be trained
to not reveal their treatment condition during the evaluation
so as not to bias the blind evaluator's ratings.
Assessor Training - The reliability and validity
of an assessment depends largely on the skill of the evaluator,
and thus training of assessors is critical and a minimum criterion
should be specified. This includes demonstrating interrater
reliability and calibrating assessment procedures over the
course of the study to prevent evaluator drift.
Manualized, Replicable, Specific Treatment Programs
- It is also important that the treatment chosen is designed
to address the target problem defined by inclusion criteria.
Thus, if PTSD is the disorder targeted for treatment, employing
a treatment specifically developed for PTSD would be most
appropriate. Detailed treatment manuals are of utmost importance
in evaluating treatment efficacy because they help to ensure
consistent treatment delivery across patients and across therapists
and afford replicability of the treatment to determine generalizability.
Unbiased Assignment to Treatment - To eliminate one
potential source of bias, neither patients nor therapists
should be allowed to choose the patient's treatment condition.
Instead, patients should be assigned randomly to treatment
condition, or assigned via a stratified sampling approach.
This helps to ensure that observed differences or similarities
among treatments are due to the techniques employed rather
than to extraneous factors. To separate the effects of treatment
from therapists, each treatment should be delivered by at
least two therapists, and patients should be randomly assigned
to therapists within each condition.
Treatment Adherence - The final component of a well
controlled study is the use of treatment adherence ratings.
These ratings inform as to whether the treatments were carried
out as planned, and whether components of one treatment condition
drifted into another.
Limitations of Well Controlled Studies
While controlled studies are essential for evaluating the
efficacy of a given treatment approach, the data emerging
from such studies is by no means without problems. The stringent
requirement of such studies render sometimes unrepresentative
samples and therefore the generalizablity of the results may
be limited. For example, the requirement of random assignments
to studies that include placebo, may be acceptable to some
patients but not to others and the factors that lead someone
to enroll in such studies may be germane to how well he/she
responds to treatment.
Another source of bias in knowledge derived from controlled
studies is that certain treatment approaches are more amenable
for such studies than others. For example, short-term and
structured treatments such as cognitive behavior therapy and
medication, are more suitable for controlled trials than longer,
less structured treatments. As a result, knowledge about the
efficacy of the former is more available that of the latter.
CODING SYSTEM
To help the clinician in evaluating the treatment approaches
presented in the guideline, the following coding system was
devised to denote the strength of the evidence for each approach.
Each recommendation is identified as falling into one of
six categories of endorsements, each indicated by a letter.
The six categories represent varying levels of evidence for
the use of a specific treatment procedure, or for a specific
recommendation. This system was adopted from the Agency of
Health Care Policy and Research (AHCPR) classification of
Level of Evidence.
Level A: evidence is based upon randomized controlled
clinical trials for individuals with PTSD.
Level B: evidence is based upon well designed clinical
studies without randomization or placebo comparison for individuals
with PTSD.
Level C: evidence is based on service and naturalistic
clinical studies, combined with clinical observations, which
are sufficiently compelling to warrant use of the treatment
technique or follow the specific recommendation.
Level D: evidence is based on long-standing and wide-spread
clinical practice that has not been subjected to empirical
tests in PTSD.
Level E: evidence is based on long-standing practice
by circumscribed groups of clinicians that has not been subjected
to empirical tests in PTSD.
Level F: evidence is based on recently developed
treatment that has not been subjected to clinical or empirical
tests in PTSD.
TREATMENT CONSIDERATIONS
Therapist Training
To most appropriately utilize the information contained in
this guideline, individuals should be professionally trained
and licensed clinically in their state or country. Typical
training would include a graduate level degree, a clinical
internship or its equivalent, and past supervision in the
specific technique or approach employed.
Choice of Treatment Setting
Most treatments for PTSD take place in an outpatient setting
such as psychiatric or psychological clinics and counseling
centers. However, an inpatient setting is required when the
patient manifests a significant tendency for suicidality,
or severe comorbid disorders (e.g., psychotic episode, severe
borderline personality). The treatment setting should be determined
during the initial diagnostic evaluation. Careful monitoring
of the patient's mental status throughout treatment may indicate
the appropriateness of changes in the treatment setting.
Treatment Management
A comprehensive diagnostic evaluation should precede treatment
to determine the presence of PTSD and whether PTSD symptoms
constitute the predominant problem of the patient. Once the
diagnosis is ascertained, irrespective of the treatment chosen,
the clinician should establish a professional milieu. First,
the clinician must form and maintain a therapeutic alliance.
Special attention should be given to trust and safety issues.
Many individuals with PTSD have difficulties trusting others,
especially if the trauma had interpersonal aspects (e.g.,
assault, rape). Therefore, during the first stage of therapy,
attention should be directed to this sensitive issue, providing
reassurance that the patient's welfare is the priority in
the therapeutic relationship. Second, the therapist should
demonstrate concern with the patient's physical safety when
planning the treatment, such as appraising the safety of places
selected for exposure exercises, or monitoring the safety
of the woman who had just left an abusive relationship. Third,
the clinician should provide education and reassurance with
regard to the PTSD symptoms and related problems. Fourth,
the patient's PTSD symptoms and general functioning should
be monitored over time. Fifth, comorbid conditions should
be identified and addressed. When necessary, it is important
to work with other health professionals and with the patient's
family members and significant others. Many patients with
PTSD require dependable and steady therapeutic relationships
because their symptoms do not remit completely and can exacerbate
with trauma reminders. For these reasons it is important to
assure the patient of the continued availability of his or
her therapist.
The State of Current Knowledge About Treatment of PTSD
Research on treatment efficacy for PTSD began in the early
1980’s, with the introduction of the disorder into the DSM-III.
Since then many case reports and studies have been published.
These studies vary with respect to their methodological rigor
and therefore, the strength of conclusions that can be drawn
from them. In general, psychotherapy, specifically cognitive
behavioral therapy (CBT), and medication, specifically SSRIs,
have both been shown to be effective treatments for PTSD.
There is some research evidence that psychodynamic psychotherapy,
hypnotherapy, and EMDR are also effective, but the studies
are either less numerous or less controlled.
Combined Treatments
There are no studies that systematically examined the value
of combining psychotherapy with medication, or combinations
of medications. Research on other disorders (e.g., depression)
has shown benefits from combination approaches. Only a couple
of studies examine whether programs that include a wide variety
of cognitive behavioral therapy techniques yield better outcome
over programs that include fewer techniques. On the whole,
these studies do not support the administering of more complex
programs. Despite the scarcity of knowledge, clinical wisdom
dictates the use of combined treatments for some patients.
Many patients with PTSD also suffer from depression. If the
depression is moderate to severe, a combination of psychotherapy
and medication is often desired.
Treatment Resistance
Despite the progress that has been achieved in the treatment
of PTSD, many patients do not benefit from the first line
of treatment. The phenomenon of treatment resistance has been
particularly noted among Vietnam veterans receiving VA treatment
in the U.S., but other trauma populations have their share
of treatment failures. It seems that patients with pervasive
dysfunction and/or high comorbidity are especially resistant
to first line therapy. These patients are especially good
candidates for programs that include multiple treatment modalities
such as mediation, psychotherapy, family therapy, and rehabilitation
therapy.
Readiness for treatment
Many traumatized individuals with acute PTSD do not seek
treatment for the disorder because they assume that the symptoms
will dissipate with time. Attempts to offer treatment in this
initial stage often fail. Even when PTSD becomes chronic,
many sufferers do not seek treatment or present to treatment
with related symptoms such as depression. Therefore, after
diagnosing the disorder, a crucial first step in preparing
the patient for treatment of PTSD is educating him/her about
the disorder and about its high rates among trauma survivors.
Many sufferers are reluctant to enter treatment because they
view their PTSD symptoms as a personal failure. For most patients,
the normalizing of their symptoms results in an immediate
relief and reduces their reluctance to enter treatment.
Some patients are reluctant to enter treatment because it
often entails discussing the traumatic event either during
the assessment or in therapy. The clinician should encourage
the patient to express his/her misgivings and be sensitive
to the distress patients experience when discussing or recounting
their traumatic experiences so that they can be addressed
in the first stage of therapy.
Validity of Memories of Traumatic Events
To receive the diagnosis of PTSD, one must first be exposed
to a traumatic event. Treatment of PTSD typically involves
the processing of this event, its meaning, and its consequences.
All the methods in the guideline presuppose the existence
of a verifiable and valid traumatic event. The guideline does
not address the use of any of these approaches in an effort
to recover unconscious memories of past traumatic events.
The Task Force does acknowledge that memories for traumatic
events are sometimes not reported or are forgotten by individuals
who seek mental health treatment (see Roth & Friedman,
1998). Yet, because of lack of scientific evidence, the Task
Force does not support the position that the presence
of some of the symptoms of PTSD (e.g. emotional numbing, concentration
problems, etc.) are clear evidence that the patient had experienced
a traumatic event. Therefore, the Task Force does not support
the use of this guideline to assist in the recovery of forgotten
traumatic memories.
How to Use the Guideline
This guideline summarizes the state of the art in the treatment
of PTSD to inform mental health professionals of the care
of patients with PTSD. It begins at the point where the patient
has been diagnosed as having this disorder according to the
criteria in DSM-IV. The guideline also assumes that the patient
has been evaluated for co-morbid disorders. The guideline
includes treatments with various degrees of evidence for their
efficacy and this is indicated by the coding system described
earlier. The clinician is encouraged to adopt treatments that
have been proven effective. However, it is important to remember
that several treatments of about equal efficacy (e.g., medication,
CBT) are available. Also, many treatments that have not been
evaluated in well controlled studies have been practiced extensively
and thus, have accumulated clinical evidence for their efficacy.
In addition, the choice of treatment approach should be decided
by the clinical circumstances presented by the specific patient
(e.g., the presence of comorbid disorders) as well as by the
efficacy of the treatment modality.

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