El comite por la seguridad farmacológica del Ministerio de Salud Inglés ha encomendado un trabajo sobre el uso de la olanzapina y la risperidona en pacientes con demencia. La conclusiones a las que llega se agregan en este linkAtypical antipsychotic drugs and stroke

Prescribing advice
CSM has advised that risperidone or olanzapine should not be used for the treatment of behavioural symptoms of dementia.
Use of risperidone for the management of acute psychotic conditions in elderly patients who also have dementia should be limited to short-term and should be under specialist advice (olanzapine is not licensed for management of acute psychoses).
Prescribers should consider carefully the risk of cerebrovascular events before treating any patient with a previous history of stroke or transient ischaemic attack. Consideration should also be given to other risk factors for cerebrovascular disease including hypertension, diabetes, current smoking and atrial fibrillation.